35SZ

Structure of the Ntn hydrolase NcdG from nocardichelin biosynthesis

Summary for 35SZ

• Entry DOI: 10.2210/pdb35sz/pdb
• Descriptor: Penicillin acylase family protein, alpha chain, Penicillin acylase family protein, beta chain, DI(HYDROXYETHYL)ETHER, ... (6 entities in total)
• Functional Keywords: hydrolase ntn hydrolase siderophore biosynthesis n-hydroxy-n-succinylcadaverine succinylase, hydrolase
• Biological source: Nocardia carnea NBRC 14403; More
• Total number of polymer chains: 4
• Total formula weight: 168623.29

Authors

Fisk, M.B.,Gulick, A.M. (deposition date: 2026-05-15, release date: 2026-08-26)

• Primary citation: Fisk, M.B.,Merrick, C.E.,Wencewicz, T.A.,Gulick, A.M.; The Biosynthetic Pathway for the Hybrid NRPS-NIS Siderophore Nocardichelin Contains NcdG, a Succinylase that Cleaves the Hydroxamate Bond of the Acylcadaverine Intermediate; Acs Chem.Biol., 2026; DOI: 10.1021/acschembio.6c00490

Experimental method

X-RAY DIFFRACTION (2.25 Å)