31HP

Crystal structure of tau tubulin kinase 2 (TTBK2) in complex with compound 62

This is a non-PDB format compatible entry.

Summary for 31HP

• Entry DOI: 10.2210/pdb31hp/pdb
• Descriptor: Tau-tubulin kinase 2, ~{N}-[4-(furan-2-yl)phenyl]-7~{H}-pyrrolo[2,3-d]pyrimidin-4-amine, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: tau and tubulin kinase, inhibitor, drug design, brain-penetrant inhibitor, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 35364.70

Authors

Zhubi, R.,Sanchez-Santos, C.,Martinez, A.,Knapp, S.,Joerger, A.C.,Structural Genomics Consortium (SGC) (deposition date: 2026-06-04, release date: 2026-07-29)

• Primary citation: Zhubi, R.,Sanchez-Santos, C.,Martinez, A.,Knapp, S.,Joerger, A.C.,Structural Genomics Consortium (SGC); Crystal structure of TTBK2 kinase in complex with compound 62; to be published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)