30TR

14-3-3sigma protein binding to TSC2-weak peptide (AAA mutation)

Summary for 30TR

Entry DOI	10.2210/pdb30tr/pdb
Descriptor	14-3-3 protein sigma, TSC2 peptide pS1254 weak mutant, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	14-3-3, peptide-protein interaction, tsc2, peptide binding protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	27435.14
Authors	Pennings, M.A.M.,Brunsveld, L. (deposition date: 2026-05-13, release date: 2026-08-26)
Primary citation	Pennings, M.A.M.,Vandenboorn, E.M.F.,Nooren, L.,Ottmann, C.,Brunsveld, L. Mechanistic Insights into Molecular Glue Cooperativity: A 14-3-3 Case Study To Be Published,
Experimental method	X-RAY DIFFRACTION (1.3 Å)

Structure validation