30GH

CryoEM structure of human MATa2 in complex with MAT2B isoform v1 at 2.6 A resolution

Summary for 30GH

• Entry DOI: 10.2210/pdb30gh/pdb
• EMDB information: 57756
• Descriptor: S-adenosylmethionine synthase isoform type-2, Isoform 1 of Methionine adenosyltransferase 2 subunit beta (2 entities in total)
• Functional Keywords: methylation, adomet, same, protein-protein complexes, transferase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 250090.06

Authors

Khaja, F.,Antonyuk, S.V.,Muench, S.P.,Hasnain, S.S. (deposition date: 2026-04-23, release date: 2026-05-13)

• Primary citation: Khaja, F.,Vara, R.,Aspinall, L.P.,Merriman, C.,Maerivoet, A.,White, J.B.R.,Muench, S.P.,Hasnain, S.S.,Antonyuk, S.V.; High resolution cryoEM structures reveal allosteric regulation of the catalytic activity of the multi-protein human MAT enzyme complexes; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.1 Å)