2ZZP

The crystal structure of human Atg4B(C74S)- LC3(1-124) complex

2ZZP の概要

• エントリーDOI: 10.2210/pdb2zzp/pdb
• 分子名称: Cysteine protease ATG4B, Microtubule-associated proteins 1A/1B light chain 3B (3 entities in total)
• 機能のキーワード: papain-like fold, ubiquitin fold, alternative splicing, autophagy, cytoplasm, hydrolase, phosphoprotein, polymorphism, protease, protein transport, thiol protease, transport, ubl conjugation pathway, cytoplasmic vesicle, lipoprotein, membrane, microtubule, hydrolase-structural protein complex, hydrolase/structural protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm (Probable): Q9Y4P1; Cytoplasm, cytoskeleton: Q62625
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 55094.77

構造登録者

Satoo, K.,Noda, N.N.,Inagaki, F. (登録日: 2009-02-22, 公開日: 2009-03-03, 最終更新日: 2023-11-01)

• 主引用文献: Satoo, K.,Noda, N.N.,Kumeta, H.,Fujioka, Y.,Mizushima, N.,Ohsumi, Y.,Inagaki, F.; The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy.; Embo J., 28:1341-1350, 2009; PubMed: 19322194; DOI: 10.1038/emboj.2009.80

実験手法

X-RAY DIFFRACTION (2.05 Å)