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2ZYQ

Crystal structure of the HsaC extradiol dioxygenase from M. tuberculosis

Summary for 2ZYQ
Entry DOI10.2210/pdb2zyq/pdb
Related2ZI8
DescriptorPROBABLE BIPHENYL-2,3-DIOL 1,2-DIOXYGENASE BPHC, FE (II) ION, D(-)-TARTARIC ACID, ... (4 entities in total)
Functional Keywordsdioxygenase, extradiol, dhsa, tb, catechol, cholesterol, steroid, aromatic hydrocarbons catabolism, iron, oxidoreductase
Biological sourceMycobacterium tuberculosis
Total number of polymer chains2
Total formula weight67518.40
Authors
D'Angelo, I.,Yam, K.C.,Eltis, L.D.,Strynadka, N. (deposition date: 2009-01-28, release date: 2009-03-10, Last modification date: 2023-11-01)
Primary citationYam, K.C.,D'Angelo, I.,Kalscheuer, R.,Zhu, H.,Wang, J.X.,Snieckus, V.,Ly, L.H.,Converse, P.J.,Jacobs, W.R.,Strynadka, N.,Eltis, L.D.
Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis.
Plos Pathog., 5:e1000344-e1000344, 2009
Cited by
PubMed: 19300498
DOI: 10.1371/journal.ppat.1000344
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

217705

数据于2024-03-27公开中

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