2ZX6
alpha-L-fucosidase complexed with inhibitor, F10-1C
Summary for 2ZX6
Entry DOI | 10.2210/pdb2zx6/pdb |
Related | 1hl8 2zwy 2zwz 2ZX5 2ZX7 2ZX8 2ZX9 2ZXA 2ZXB 2ZXD |
Descriptor | Alpha-L-fucosidase, putative, 2-(1H-indol-3-yl)-N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}acetamide (3 entities in total) |
Functional Keywords | tim barrel, hydrolase |
Biological source | Thermotoga maritima |
Total number of polymer chains | 2 |
Total formula weight | 106868.60 |
Authors | Wu, H.-J.,Ko, T.-P.,Ho, C.-W.,Lin, C.-H.,Wang, A.H.-J. (deposition date: 2008-12-19, release date: 2009-12-08, Last modification date: 2023-11-01) |
Primary citation | Wu, H.J.,Ho, C.W.,Ko, T.P.,Popat, S.D.,Lin, C.H.,Wang, A.H. Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range. Angew.Chem.Int.Ed.Engl., 49:337-340, 2010 Cited by PubMed: 19967696DOI: 10.1002/anie.200905597 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.42 Å) |
Structure validation
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