2ZVN

NEMO CoZi domain incomplex with diubiquitin in P212121 space group

Summary for 2ZVN

• Entry DOI: 10.2210/pdb2zvn/pdb
• Related: 2ZVO 3F89
• Descriptor: UBC protein, NF-kappa-B essential modulator (3 entities in total)
• Functional Keywords: nf-kb signaling, ubiquitin binding, coiled coil, cytoplasm, metal-binding, nucleus, phosphoprotein, transcription, transcription regulation, ubl conjugation, zinc, zinc-finger, signaling protein-transcription complex, signaling protein/transcription
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm : O88522
• Total number of polymer chains: 8
• Total formula weight: 110398.05

Authors

Rahighi, S.,Ikeda, F.,Kawasaki, M.,Akutsu, M.,Suzuki, N.,Kato, R.,Kensche, T.,Uejima, T.,Bloor, S.,Komander, D.,Randow, F.,Wakatsuki, S.,Dikic, I. (deposition date: 2008-11-12, release date: 2009-03-24, Last modification date: 2024-03-13)

• Primary citation: Rahighi, S.,Ikeda, F.,Kawasaki, M.,Akutsu, M.,Suzuki, N.,Kato, R.,Kensche, T.,Uejima, T.,Bloor, S.,Komander, D.,Randow, F.,Wakatsuki, S.,Dikic, I.; Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation; Cell(Cambridge,Mass.), 136:1098-1109, 2009; PubMed: 19303852; DOI: 10.1016/j.cell.2009.03.007

Experimental method

X-RAY DIFFRACTION (3 Å)