2ZV9

Lyn Tyrosine Kinase Domain-PP2 complex

Summary for 2ZV9

Entry DOI	10.2210/pdb2zv9/pdb
Related	2ZV7 2ZV8 2ZVA
Descriptor	Tyrosine-protein kinase Lyn, 1-TERT-BUTYL-3-(4-CHLORO-PHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE (3 entities in total)
Functional Keywords	lyn kinase pp2, alternative splicing, atp-binding, kinase, lipoprotein, myristate, nucleotide-binding, palmitate, phosphoprotein, proto-oncogene, sh2 domain, sh3 domain, transferase, tyrosine-protein kinase
Biological source	Mus musculus (mouse)
Cellular location	Cell membrane (By similarity): P25911
Total number of polymer chains	1
Total formula weight	32113.42
Authors	Williams, N.K.,Rossjohn, J. (deposition date: 2008-11-04, release date: 2008-11-11, Last modification date: 2023-11-01)
Primary citation	Williams, N.K.,Lucet, I.S.,Klinken, S.P.,Ingley, E.,Rossjohn, J. Crystal Structures of the Lyn Protein Tyrosine Kinase Domain in Its Apo- and Inhibitor-bound State J.Biol.Chem., 284:284-291, 2009 Cited by PubMed: 18984583 DOI: 10.1074/jbc.M807850200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.76 Å)

Structure validation