2ZTX

Complex structure of CVB3 3C protease with EPDTC

Summary for 2ZTX

Entry DOI	10.2210/pdb2ztx/pdb
Related	2ZTY 2ZTZ 2ZU1 2ZU2 2ZU3 2ZU4 2ZU5
Descriptor	3C proteinase, zinc(II)hydrogensulfide (3 entities in total)
Functional Keywords	protease-inhibitor complex, hydrolase, protease, thiol protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Human coxsackievirus B3
Total number of polymer chains	1
Total formula weight	20429.85
Authors	Lee, C.C.,Wang, A.H.-J. (deposition date: 2008-10-10, release date: 2009-01-13, Last modification date: 2023-11-01)
Primary citation	Lee, C.C.,Kuo, C.J.,Ko, T.P.,Hsu, M.F.,Tsui, Y.C.,Chang, S.C.,Yang, S.,Chen, S.J.,Chen, H.C.,Hsu, M.C.,Shih, S.R.,Liang, P.H.,Wang, A.H.-J. Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds J.Biol.Chem., 284:7646-7655, 2009 Cited by PubMed: 19144641 DOI: 10.1074/jbc.M807947200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.72 Å)

Structure validation