2ZTX

Complex structure of CVB3 3C protease with EPDTC

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004197	molecular_function	cysteine-type endopeptidase activity
A	0006508	biological_process	proteolysis

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE DTZ A 501

Chain	Residue
A	PHE25
A	HIS40
A	CYS147
A	HOH321
A	HOH401

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: For protease 3C activity => ECO:0000255|PROSITE-ProRule:PRU01222

Chain	Residue	Details
A	HIS40
A	GLU71

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: For protease 3C activity => ECO:0000269|PubMed:33691586

Chain	Residue	Details
A	CYS147

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site_id	SWS_FT_FI3
Number of Residues	1
Details	SITE: Cleavage; by protease 3C => ECO:0000250|UniProtKB:P03301

Chain	Residue	Details
A	GLN183

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1cqq

Chain	Residue	Details
A	GLY145
A	HIS40
A	GLU71
A	CYS147

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