2ZN8

Crystal structure of Zn2+-bound form of ALG-2

Summary for 2ZN8

Entry DOI	10.2210/pdb2zn8/pdb
Related	2ZN9 2ZND 2ZNE
Descriptor	Programmed cell death protein 6, ZINC ION, SODIUM ION, ... (4 entities in total)
Functional Keywords	penta-ef-hand protein, calcium binding protein, apoptosis, calcium, endoplasmic reticulum, membrane, nucleus, polymorphism
Biological source	Homo sapiens (human)
Cellular location	Nucleus membrane; Peripheral membrane protein: O75340
Total number of polymer chains	1
Total formula weight	22042.85
Authors	Suzuki, H.,Kawasaki, M.,Inuzuka, T.,Kakiuchi, T.,Shibata, H.,Wakatsuki, S.,Maki, M. (deposition date: 2008-04-22, release date: 2008-09-09, Last modification date: 2023-11-01)
Primary citation	Suzuki, H.,Kawasaki, M.,Inuzuka, T.,Okumura, M.,Kakiuchi, T.,Shibata, H.,Wakatsuki, S.,Maki, M. Structural Basis for Ca(2+)-Dependent Formation of ALG-2/Alix Peptide Complex: Ca(2+)/EF3-Driven Arginine Switch Mechanism Structure, 16:1562-1573, 2008 Cited by PubMed: 18940611 DOI: 10.1016/j.str.2008.07.012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation