2ZIM

Pyrrolysyl-tRNA synthetase bound to adenylated pyrrolysine and pyrophosphate

2ZIM の概要

• エントリーDOI: 10.2210/pdb2zim/pdb
• 関連するPDBエントリー: 2Q7E 2Q7G
• 分子名称: Pyrrolysyl-tRNA synthetase, 1,2-ETHANEDIOL, (2R)-2-AMINO-6-({[(2S,3R)-3-METHYLPYRROLIDIN-2-YL]CARBONYL}AMINO)HEXANOYL [(2S,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL HYDROGEN (R)-PHOSPHATE, ... (5 entities in total)
• 機能のキーワード: trna synthetase bound to an adenylated intermediate, aminoacyl-trna synthetase, atp-binding, ligase, nucleotide-binding, protein biosynthesis
• 由来する生物種: Methanosarcina mazei
• 細胞内の位置: Cytoplasm : Q8PWY1
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34799.40

構造登録者

Steitz, T.A.,Kavran, J.M. (登録日: 2008-02-19, 公開日: 2008-03-04, 最終更新日: 2024-02-21)

• 主引用文献: Kavran, J.M.,Gundllapalli, S.,O'Donoghue, P.,Englert, M.,Soll, D.,Steitz, T.A.; Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation.; Proc.Natl.Acad.Sci.Usa, 104:11268-11273, 2007; PubMed: 17592110; DOI: 10.1073/pnas.0704769104

実験手法

X-RAY DIFFRACTION (2.1 Å)