2ZI7

C4S dCK variant of dCK in complex with D-dG+UDP

2ZI7 の概要

• エントリーDOI: 10.2210/pdb2zi7/pdb
• 関連するPDBエントリー: 1P60 2NO1 2NO7 2ZI3 2ZI4 2ZI5 2ZI6 2ZI9 2ZIA
• 分子名称: Deoxycytidine kinase, 2'-DEOXY-GUANOSINE, URIDINE-5'-DIPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: dck, purine, deoxyguanosine, deoxycytidine kinase, nucleoside, enantiomer, d-dg, dg, atp-binding, nucleotide-binding, nucleus, phosphoprotein, transferase
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Nucleus: P27707
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 66487.82

構造登録者

Sabini, E.,Lavie, A. (登録日: 2008-02-13, 公開日: 2008-07-08, 最終更新日: 2023-11-01)

• 主引用文献: Sabini, E.,Hazra, S.,Konrad, M.,Lavie, A.; Elucidation of different binding modes of purine nucleosides to human deoxycytidine kinase; J.Med.Chem., 51:4219-4225, 2008; PubMed: 18570408; DOI: 10.1021/jm800134t

実験手法

X-RAY DIFFRACTION (1.97 Å)