2ZI7
C4S dCK variant of dCK in complex with D-dG+UDP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, A | Deoxycytidine kinase | polymer | 279 | 32572.5 | 2 | UniProt (P27707) Pfam (PF01712) In PDB | Homo sapiens (Human) | dCK |
2 | B, A | 2'-DEOXY-GUANOSINE | non-polymer | 267.2 | 2 | Chemie (GNG) | |||
3 | B, A | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 2 | Chemie (UDP) | |||
4 | water | water | 18.0 | 84 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 260 (UniProt: P27707)
PDB | External Database | Details |
---|---|---|
Met -18 | - | expression tag |
Gly -17 | - | expression tag |
Ser -16 | - | expression tag |
Ser -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Ser 9 | Cys 9 | engineered mutation |
Ser 45 | Cys 45 | engineered mutation |
Ser 59 | Cys 59 | engineered mutation |
Ser 146 | Cys 146 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 65145.0 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1342.8 | |
All* | Total formula weight | 66487.8 |