2ZHX

Crystal structure of Uracil-DNA Glycosylase from Mycobacterium tuberculosis in complex with a proteinaceous inhibitor

2ZHX の概要

• エントリーDOI: 10.2210/pdb2zhx/pdb
• 分子名称: Uracil-DNA glycosylase, Uracil-DNA glycosylase inhibitor (3 entities in total)
• 機能のキーワード: dna repair, ung-ugi complex, ung-dna interactions, dna damage, glycosidase, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Mycobacterium tuberculosis H37Rv; 詳細
• タンパク質・核酸の鎖数: 14
• 化学式量合計: 247073.52

構造登録者

Kaushal, P.S.,Talawar, R.K.,Krishna, P.D.V.,Varshney, U.,Vijayan, M. (登録日: 2008-02-11, 公開日: 2008-05-20, 最終更新日: 2023-11-01)

• 主引用文献: Kaushal, P.S.,Talawar, R.K.,Krishna, P.D.V.,Varshney, U.,Vijayan, M.; Unique features of the structure and interactions of mycobacterial uracil-DNA glycosylase: structure of a complex of the Mycobacterium tuberculosis enzyme in comparison with those from other sources; Acta Crystallogr.,Sect.D, 64:551-560, 2008; PubMed: 18453691; DOI: 10.1107/S090744490800512X

実験手法

X-RAY DIFFRACTION (3.1 Å)