2ZET

Crystal structure of the small GTPase Rab27B complexed with the Slp homology domain of Slac2-a/melanophilin

Summary for 2ZET

Entry DOI	10.2210/pdb2zet/pdb
Descriptor	Ras-related protein Rab-27B, Melanophilin, MAGNESIUM ION, ... (7 entities in total)
Functional Keywords	complex, gtp-binding protein, gtpase, g-protein, rab, rab27b, effector, melanophilin, slp homology domain, acetylation, lipoprotein, membrane, methylation, nucleotide-binding, prenylation, coiled coil, metal-binding, zinc, zinc-finger, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, signaling protein
Biological source	Mus musculus (mouse) More
Cellular location	Membrane; Lipid-anchor (By similarity): Q99P58 Melanosome: Q91V27
Total number of polymer chains	4
Total formula weight	83463.62
Authors	Kukimoto-Niino, M.,Sakamoto, A.,Kanno, E.,Hanawa-Suetsugu, K.,Terada, T.,Shirouzu, M.,Fukuda, M.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2007-12-17, release date: 2008-09-30, Last modification date: 2021-11-10)
Primary citation	Kukimoto-Niino, M.,Sakamoto, A.,Kanno, E.,Hanawa-Suetsugu, K.,Terada, T.,Shirouzu, M.,Fukuda, M.,Yokoyama, S. Structural basis for the exclusive specificity of Slac2-a/melanophilin for the Rab27 GTPases. Structure, 16:1478-1490, 2008 Cited by PubMed: 18940604 DOI: 10.1016/j.str.2008.07.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation