2ZBK

Crystal structure of an intact type II DNA topoisomerase: insights into DNA transfer mechanisms

2ZBK の概要

• エントリーDOI: 10.2210/pdb2zbk/pdb
• 分子名称: Type II DNA topoisomerase VI subunit A, Type 2 DNA topoisomerase 6 subunit B, RADICICOL (3 entities in total)
• 機能のキーワード: dna topoisomerase, dna binding protein, decatenation, atpase, drug design, dna-binding, magnesium, metal-binding, atp-binding, nucleotide-binding, structural genomics, paris-sud yeast structural genomics, ysg, isomerase
• 由来する生物種: Sulfolobus shibatae (archaea); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 424405.25

構造登録者

Graille, M.,Cladiere, L.,Durand, D.,Lecointe, F.,Forterre, P.,van Tilbeurgh, H.,Paris-Sud Yeast Structural Genomics (YSG) (登録日: 2007-10-22, 公開日: 2008-02-12, 最終更新日: 2023-11-01)

• 主引用文献: Graille, M.,Durand, D.,Lecointe, F.,Gadelle, D.,Quevillon-Cheruel, S.,Vachette, P.,Forterre, P.,van Tilbeurgh, H.; Crystal Structure of an Intact Type II DNA Topoisomerase: Insights into DNA Transfer Mechanisms; Structure, 16:360-370, 2008; PubMed: 18334211; DOI: 10.1016/j.str.2007.12.020

実験手法

X-RAY DIFFRACTION (3.56 Å)