2Z77

X-ray crystal structure of RV0760c from Mycobacterium tuberculosis in complex with estradiol-17beta-hemisuccinate

Summary for 2Z77

• Entry DOI: 10.2210/pdb2z77/pdb
• Related: 2A15 2Z76 2Z7A
• Descriptor: Putative steroid isomerase, 4-{[(14beta,17alpha)-3-hydroxyestra-1,3,5(10)-trien-17-yl]oxy}-4-oxobutanoic acid, ACETATE ION, ... (5 entities in total)
• Functional Keywords: alpha+beta conical barrel, complex with estradiol-17beta-hemisuccinate, structural genomics, tb structural genomics consortium, tbsgc, isomerase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 4
• Total formula weight: 62381.60

Authors

Cherney, M.M.,Garen, C.R.,James, M.N.G.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2007-08-16, release date: 2007-09-18, Last modification date: 2023-08-30)

• Primary citation: Cherney, M.M.,Garen, C.R.,James, M.N.; Crystal structure of Mycobacterium tuberculosis Rv0760c at 1.50 A resolution, a structural homolog of Delta(5)-3-ketosteroid isomerase.; Biochim.Biophys.Acta, 1784:1625-1632, 2008; PubMed: 18589008; DOI: 10.1016/j.bbapap.2008.05.012

Experimental method

X-RAY DIFFRACTION (2.03 Å)