2Z6K

Crystal structure of full-length human RPA14/32 heterodimer

Summary for 2Z6K

• Entry DOI: 10.2210/pdb2z6k/pdb
• Related: 2PI2 2PQA
• Descriptor: Replication protein A 32 kDa subunit, Replication protein A 14 kDa subunit (2 entities in total)
• Functional Keywords: full-length rpa14/32, ssdna binding protein, ob-fold, acetylation, alternative splicing, dna replication, nucleus, phosphorylation, polymorphism, replication
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P15927 P35244
• Total number of polymer chains: 4
• Total formula weight: 90788.50

Authors

Deng, X.,Habel, J.E.,Kabaleeswaran, V.,Borgstahl, G.E. (deposition date: 2007-08-03, release date: 2007-12-04, Last modification date: 2023-11-01)

• Primary citation: Deng, X.,Habel, J.E.,Kabaleeswaran, V.,Snell, E.H.,Wold, M.S.,Borgstahl, G.E.; Structure of the Full-length Human RPA14/32 Complex Gives Insights into the Mechanism of DNA Binding and Complex Formation; J.Mol.Biol., 374:865-876, 2007; PubMed: 17976647; DOI: 10.1016/j.jmb.2007.09.074

Experimental method

X-RAY DIFFRACTION (3 Å)