2Z6J

Crystal Structure of S. pneumoniae Enoyl-Acyl Carrier Protein Reductase (FabK) in Complex with an Inhibitor

Summary for 2Z6J

• Entry DOI: 10.2210/pdb2z6j/pdb
• Related: 2Z6I
• Descriptor: Trans-2-enoyl-ACP reductase II, CALCIUM ION, FLAVIN MONONUCLEOTIDE, ... (6 entities in total)
• Functional Keywords: fatty acid synthesis, antibiotics, oxidoreductase, flavoprotein
• Biological source: Streptococcus pneumoniae
• Total number of polymer chains: 2
• Total formula weight: 72735.09

Authors

Saito, J.,Yamada, M.,Watanabe, T.,Takeuchi, Y. (deposition date: 2007-08-01, release date: 2008-04-01, Last modification date: 2023-11-01)

• Primary citation: Saito, J.,Yamada, M.,Watanabe, T.,Iida, M.,Kitagawa, H.,Takahata, S.,Ozawa, T.,Takeuchi, Y.,Ohsawa, F.; Crystal structure of enoyl-acyl carrier protein reductase (FabK) from Streptococcus pneumoniae reveals the binding mode of an inhibitor.; Protein Sci., 17:691-699, 2008; PubMed: 18305197; DOI: 10.1110/ps.073288808

Experimental method

X-RAY DIFFRACTION (2.3 Å)