2Z2W

Human Wee1 kinase complexed with inhibitor PF0335770

2Z2W の概要

• エントリーDOI: 10.2210/pdb2z2w/pdb
• 関連するPDBエントリー: 1X8B 2IN6 2IO6
• 分子名称: Wee1-like protein kinase, CHLORIDE ION, N-[4-(2-CHLOROPHENYL)-1,3-DIOXO-1,2,3,6-TETRAHYDROPYRROLO[3,4-C]CARBAZOL-9-YL]FORMAMIDE, ... (5 entities in total)
• 機能のキーワード: wee1 kinase, inhibitor complex, transferase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus: P30291
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 32701.98

構造登録者

Squire, C.J.,Baker, E.N. (登録日: 2007-05-29, 公開日: 2008-05-06, 最終更新日: 2024-10-16)

• 主引用文献: Squire, C.J.,Baker, E.N.; Synthesis and Structure-Activity Relationships of 9-Amino-4-(2-chlorophenyl)pyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones and Related Formamides as Inhibitors of the Wee1 and Chk1 Checkpoint Kinases; To be Published,

実験手法

X-RAY DIFFRACTION (2.22 Å)