2Z2L

Penicillin-Binding Protein 2X (PBP2X) from Streptococcus pneumoniae

Summary for 2Z2L

• Entry DOI: 10.2210/pdb2z2l/pdb
• Related: 2Z2M
• Descriptor: Penicillin-binding protein 2X, SULFATE ION, ... (5 entities in total)
• Functional Keywords: peptidoglycan synthesis, cell wall, penicillin-binding, antibiotics, biosynthetic protein
• Biological source: Streptococcus pneumoniae; More
• Cellular location: Cell membrane; Single-pass membrane protein: P59676 P59676 P59676
• Total number of polymer chains: 6
• Total formula weight: 148458.13

Authors

Yamada, M.,Watanabe, T.,Takeuchi, Y. (deposition date: 2007-05-23, release date: 2007-09-04, Last modification date: 2023-11-01)

• Primary citation: Yamada, M.,Watanabe, T.,Miyara, T.,Baba, N.,Saito, J.,Takeuchi, Y.,Ohsawa, F.; Crystal Structure of Cefditoren Complexed with Streptococcus pneumoniae Penicillin-Binding Protein 2X: Structural Basis for its High Antimicrobial Activity; Antimicrob.Agents Chemother., 51:3902-3907, 2007; PubMed: 17724158; DOI: 10.1128/AAC.00743-07

Experimental method

X-RAY DIFFRACTION (2.85 Å)