2YZ1

Crystal structure of the ligand-binding domain of murine SHPS-1/SIRP alpha

2YZ1 の概要

• エントリーDOI: 10.2210/pdb2yz1/pdb
• 分子名称: Tyrosine-protein phosphatase non-receptor type substrate 1 (2 entities in total)
• 機能のキーワード: beta-sandwich, structural genomics, nppsfa, national project on protein structural and functional analyses, alternative splicing, glycoprotein, immunoglobulin domain, membrane, phosphorylation, polymorphism, sh3-binding, transmembrane, immune system
• 由来する生物種: Mus musculus (house mouse)
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P97797
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 26027.23

構造登録者

Nakaishi, A. (登録日: 2007-05-02, 公開日: 2007-12-11, 最終更新日: 2011-07-13)

• 主引用文献: Nakaishi, A.,Hirose, M.,Yoshimura, M.,Oneyama, C.,Saito, K.,Kuki, N.,Matsuda, M.,Honma, N.,Ohnishi, H.,Matozaki, T.,Okada, M.,Nakagawa, A.; Structural insight into the specific interaction between murine SHPS-1/SIRP alpha and its ligand CD47; J.Mol.Biol., 375:650-660, 2008; PubMed: 18045614; DOI: 10.1016/j.jmb.2007.10.085

実験手法

X-RAY DIFFRACTION (1.4 Å)