2YPZ

KSHV LANA (ORF73) C-terminal domain, decameric ring: orthorhombic crystal form

2YPZ の概要

• エントリーDOI: 10.2210/pdb2ypz/pdb
• 関連するPDBエントリー: 2YPY 2YQ0 2YQ1
• 分子名称: KSHV LANA (1 entity in total)
• 機能のキーワード: viral protein, latency-associated nuclear antigen, lana-1, dna-binding domain, origin-binding domain, oligomerization domain, kaposi's sarcoma-associated herpesvirus, gammaherpesvirus, rhadinovirus, primary effusion lymphoma, multicentric castleman's disease, tumor virus, cancer, murid herpesvirus 4, muhv-4, murid herpesvirus 68, mhv-68
• 由来する生物種: HUMAN HERPESVIRUS 8 TYPE M
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 157602.01

構造登録者

Hellert, J.,Krausze, J.,Luhrs, T. (登録日: 2012-11-02, 公開日: 2013-11-13, 最終更新日: 2023-12-20)

• 主引用文献: Hellert, J.,Weidner-Glunde, M.,Krausze, J.,Richter, U.,Adler, H.,Fedorov, R.,Pietrek, M.,Ruckert, J.,Ritter, C.,Schulz, T.F.,Luhrs, T.; A Structural Basis for Brd2/4-Mediated Host Chromatin Interaction and Oligomer Assembly of Kaposi Sarcoma-Associated Herpesvirus and Murine Gammaherpesvirus Lana Proteins.; Plos Pathog., 9:3640-, 2013; PubMed: 24146614; DOI: 10.1371/JOURNAL.PPAT.1003640

実験手法

X-RAY DIFFRACTION (3.199 Å)