2YPK

Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms

2YPK の概要

• エントリーDOI: 10.2210/pdb2ypk/pdb
• 関連するPDBエントリー: 2YPL
• 分子名称: HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN, BETA-2-MICROGLOBULIN, KF11 P24 GAG PEPTIDE, ... (4 entities in total)
• 機能のキーワード: immune system, micropolymorphism
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P18465; Secreted: P61769; Capsid protein p24: Virion (By similarity). Integrase: Virion. Matrix protein p17: Virion (By similarity). Matrix protein p17: Virion. Nucleocapsid protein p7: Virion (By similarity). Reverse transcriptase/ribonuclease H: Virion (By similarity): Q70XD7
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 44524.63

構造登録者

Stewart-Jones, G.B.,Simpson, P.,Van Der Merwe, P.A.,Easterbrook, P.,Mcmichael, A.J.,Rowland-Jones, S.L.,Jones, E.Y.,Gillespie, G.M. (登録日: 2012-10-30, 公開日: 2012-11-28, 最終更新日: 2023-12-20)

• 主引用文献: Stewart-Jones, G.B.,Simpson, P.,Anton Van Der Merwe, P.,Easterbrook, P.,Mcmichael, A.J.,Rowland-Jones, S.L.,Jones, E.Y.,Gillespie, G.M.; Structural Features Underlying T-Cell Receptor Sensitivity to Concealed Mhc Class I Micropolymorphisms.; Proc.Natl.Acad.Sci.USA, 109:E3483-, 2012; PubMed: 23161907; DOI: 10.1073/PNAS.1207896109

実験手法

X-RAY DIFFRACTION (1.95 Å)