2YPG

Haemagglutinin of 1968 Human H3N2 Virus in Complex with Human Receptor Analogue LSTc

Summary for 2YPG

• Entry DOI: 10.2210/pdb2ypg/pdb
• Descriptor: HEMAGGLUTININ HA1 CHAIN, CITRATE ANION, HEMAGGLUTININ HA2 CHAIN, ... (11 entities in total)
• Functional Keywords: viral protein, receptor binding, membrane fusion, influenza virus evolution, glycoprotein
• Biological source: INFLUENZA A VIRUS (A/X-31(H3N2)); More
• Cellular location: Virion membrane; Single-pass type I membrane protein (Potential): P03437 P03437
• Total number of polymer chains: 6
• Total formula weight: 179684.45

Authors

Liu, J.,Xiong, X.,Haire, L.F.,Lin, Y.P.,Wharton, S.A.,Martin, S.R.,Coombs, P.J.,Vachieri, S.G.,Christodoulou, E.,Walker, P.A.,Skehel, J.J.,Gamblin, S.J.,Hay, A.J.,Daniels, R.S.,McCauley, J.W. (deposition date: 2012-10-30, release date: 2012-11-07, Last modification date: 2020-07-29)

• Primary citation: Lin, Y.P.,Xiong, X.,Wharton, S.A.,Martin, S.R.,Coombs, P.J.,Vachieri, S.G.,Christodoulou, E.,Walker, P.A.,Liu, J.,Skehel, J.J.,Gamblin, S.J.,Hay, A.J.,Daniels, R.S.,Mccauley, J.W.; Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.; Proc.Natl.Acad.Sci.USA, 109:21474-, 2012; PubMed: 23236176; DOI: 10.1073/PNAS.1218841110

Experimental method

X-RAY DIFFRACTION (2.85 Å)