2YNB

Crystal structure of the main protease of coronavirus HKU4 in complex with a Michael acceptor SG85

Summary for 2YNB

• Entry DOI: 10.2210/pdb2ynb/pdb
• Related: 2YNA
• Descriptor: 3C-LIKE PROTEINASE, NICKEL (II) ION, N-[(benzyloxy)carbonyl]-O-tert-butyl-L-seryl-N-{(2R)-5-ethoxy-5-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]pentan-2-yl}-L-phenylalaninamide, ... (4 entities in total)
• Functional Keywords: hydrolase, sars, michael acceptor
• Biological source: TYLONYCTERIS BAT CORONAVIRUS HKU4
• Total number of polymer chains: 2
• Total formula weight: 67211.88

Authors

Ma, Q.,Xiao, Y.,Hilgenfeld, R. (deposition date: 2012-10-13, release date: 2013-10-23, Last modification date: 2019-05-15)

• Primary citation: Ma, Q.,Xiao, Y.,Hilgenfeld, R.; Inhibitor for the Main Protease of Coronavirus Hku4; To be Published,

Experimental method

X-RAY DIFFRACTION (1.96 Å)