2YLM
Mechanism of USP7 (HAUSP) activation by its C-terminal ubiquitin-like domain (HUBL) and allosteric regulation by GMP-synthetase.
Summary for 2YLM
Entry DOI | 10.2210/pdb2ylm/pdb |
Related | 1NB8 1NBF 2F1W 2F1X 2F1Y 2F1Z 2FOJ 2FOO 2FOP 2XXN |
Descriptor | UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7, CHLORIDE ION (3 entities in total) |
Functional Keywords | hydrolase, ubl |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Nucleus: Q93009 |
Total number of polymer chains | 1 |
Total formula weight | 61964.89 |
Authors | Faesen, A.C.,Perrakis, A.,Sixma, T.K. (deposition date: 2011-06-03, release date: 2011-10-19, Last modification date: 2024-05-08) |
Primary citation | Faesen, A.C.,Dirac, A.M.G.,Shanmugham, A.,Ovaa, H.,Perrakis, A.,Sixma, T.K. Mechanism of Usp7/Hausp Activation by its C- Terminal Ubiquitin-Like Domain and Allosteric Regulation by Gmp-Synthetase Mol.Cell, 44:147-, 2011 Cited by PubMed: 21981925DOI: 10.1016/J.MOLCEL.2011.06.034 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
Download full validation report