2YGP

WIF domain-EGF-like domain 1 Met77Trp of human Wnt inhibitory factor 1 in complex with 1,2-dipalmitoylphosphatidylcholine

Summary for 2YGP

Entry DOI	10.2210/pdb2ygp/pdb
Related	2YGN 2YGO 2YGQ
Descriptor	WNT INHIBITORY FACTOR 1, 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	signaling protein, wnt signaling pathway, wnt antagonist, morphogen, cancer, glycosaminoglycan
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Secreted: Q9Y5W5
Total number of polymer chains	1
Total formula weight	22271.65
Authors	Malinauskas, T.,Aricescu, A.R.,Lu, W.,Siebold, C.,Jones, E.Y. (deposition date: 2011-04-19, release date: 2011-07-13, Last modification date: 2020-07-29)
Primary citation	Malinauskas, T.,Aricescu, A.R.,Lu, W.,Siebold, C.,Jones, E.Y. Modular Mechanism of Wnt Signaling Inhibition by Wnt Inhibitory Factor 1 Nat.Struct.Mol.Biol., 18:886-, 2011 Cited by PubMed: 21743455 DOI: 10.1038/NSMB.2081 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.222 Å)

Structure validation