2YDO

Thermostabilised HUMAN A2a Receptor with adenosine bound

Summary for 2YDO

Entry DOI	10.2210/pdb2ydo/pdb
Related	1MMH 1UPE 2YDV
Descriptor	ADENOSINE RECEPTOR A2A, ADENOSINE, octyl 1-thio-beta-D-glucopyranoside, ... (4 entities in total)
Functional Keywords	receptor, g protein coupled receptor, seven-helix receptor, agonist bound form, thermostabilising point mutations, gpcr, 7tm receptor
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	36906.88
Authors	Lebon, G.,Warne, T.,Edwards, P.C.,Bennett, K.,Langmead, C.J.,Leslie, A.G.W.,Tate, C.G. (deposition date: 2011-03-23, release date: 2011-05-18, Last modification date: 2023-12-20)
Primary citation	Lebon, G.,Warne, T.,Edwards, P.C.,Bennett, K.,Langmead, C.J.,Leslie, A.G.W.,Tate, C.G. Agonist-Bound Adenosine A(2A) Receptor Structures Reveal Common Features of Gpcr Activation. Nature, 474:521-, 2011 Cited by PubMed: 21593763 DOI: 10.1038/NATURE10136 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation