2YDO
Thermostabilised HUMAN A2a Receptor with adenosine bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ADENOSINE RECEPTOR A2A | polymer | 325 | 36022.8 | 1 | UniProt (P29274) Pfam (PF00001) | HOMO SAPIENS (HUMAN) | THERMOSTABILISED HUMAN A2A RECEPTOR |
| 2 | B (A) | ADENOSINE | non-polymer | 267.2 | 1 | Chemie (ADN) | |||
| 3 | C, D (A) | octyl 1-thio-beta-D-glucopyranoside | non-polymer | 308.4 | 2 | Chemie (SOG) PubChem (20765008) PubChem (22840433) PubChem (3035440) PubChem (24802438) PubChem (24802439) PubChem (363418) PubChem (44120068) PubChem (446404) PubChem (46782626) PubChem (656909) PubChem (53720324) PubChem (53720325) PubChem (53720326) PubChem (53720327) PubChem (89711063) PubChem (92151891) PubChem (95858717) PubChem (95858718) PubChem (96327603) PubChem (96367497) PubChem (96367498) PubChem (98118655) PubChem (97944776) PubChem (101682121) PubChem (102041106) PubChem (124524845) PubChem (171395924) | |||
| 4 | E (A) | water | water | 18.0 | 18 | Chemie (HOH) |
Sequence modifications
A: 1 - 317 (UniProt: P29274)
| PDB | External Database | Details |
|---|---|---|
| Ala 48 | Leu 48 | engineered mutation |
| Leu 54 | Ala 54 | engineered mutation |
| Ala 65 | Thr 65 | engineered mutation |
| Ala 89 | Gln 89 | engineered mutation |
| Ala 154 | Asn 154 | engineered mutation |
| Ala 318 | - | expression tag |
| Ala 319 | - | expression tag |
| Glu 320 | - | expression tag |
| Asn 321 | - | expression tag |
| Leu 322 | - | expression tag |
| Tyr 323 | - | expression tag |
| Phe 324 | - | expression tag |
| Gln 325 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36022.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 884.1 | |
| All* | Total formula weight | 36906.9 |
