2YCN

Y71F mutant of tyrosine phenol-lyase from Citrobacter freundii in complex with quinonoid intermediate formed with 3-fluoro-L-tyrosine

2YCN の概要

• エントリーDOI: 10.2210/pdb2ycn/pdb
• 関連するPDBエントリー: 1TPL 2EZ1 2EZ2 2TPL 2VLF 2VLH 2YCP 2YCT
• 分子名称: TYROSINE PHENOL-LYASE, POTASSIUM ION, (2E)-3-(3-fluoro-4-hydroxyphenyl)-2-{[(Z)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4(1H)-ylidene}methyl]imino}propanoic acid, ... (6 entities in total)
• 機能のキーワード: lyase, pyridoxal 5'-phosphate dependent enzyme, beta-elimination
• 由来する生物種: CITROBACTER FREUNDII
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 104336.72

構造登録者

Milic, D.,Demidkina, T.V.,Faleev, N.G.,Phillips, R.S.,Matkovic-Calogovic, D.,Antson, A.A. (登録日: 2011-03-16, 公開日: 2011-09-14, 最終更新日: 2023-12-20)

• 主引用文献: Milic, D.,Demidkina, T.V.,Faleev, N.G.,Phillips, R.S.,Matkovic-Calogovic, D.,Antson, A.A.; Crystallographic Snapshots of Tyrosine Phenol-Lyase Show that Substrate Strain Plays a Role in C-C Bond Cleavage; J.Am.Chem.Soc., 133:16468-, 2011; PubMed: 21899319; DOI: 10.1021/JA203361G

実験手法

X-RAY DIFFRACTION (2.04 Å)