2YBY

Structure of domains 6 and 7 of the mouse complement regulator Factor H

2YBY の概要

• エントリーDOI: 10.2210/pdb2yby/pdb
• 分子名称: COMPLEMENT FACTOR H, 1,2-ETHANEDIOL (3 entities in total)
• 機能のキーワード: immune system, complement regulation, innate immunity, infection
• 由来する生物種: MUS MUSCULUS (HOUSE MOUSE)
• 細胞内の位置: Secreted: P06909
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14447.17

構造登録者

Everett, R.J.,Caesar, J.J.E.,Johnson, S.J.,Tang, C.M.,Lea, S.M. (登録日: 2011-03-30, 公開日: 2012-04-18, 最終更新日: 2023-12-20)

• 主引用文献: Johnson, S.,Tan, L.,Van Der Veen, S.,Caesar, J.,Goicoechea De Jorge, E.,Harding, R.J.,Bai, X.,Exley, R.M.,Ward, P.N.,Ruivo, N.,Trivedi, K.,Cumber, E.,Jones, R.,Newham, L.,Staunton, D.,Ufret-Vincenty, R.,Borrow, R.,Pickering, M.C.,Lea, S.M.,Tang, C.M.; Design and Evaluation of Meningococcal Vaccines Through Structure-Based Modification of Host and Pathogen Molecules.; Plos Pathog., 8:2981-, 2012; PubMed: 23133374; DOI: 10.1371/JOURNAL.PPAT.1002981

実験手法

X-RAY DIFFRACTION (1.58 Å)