2Y3Y

Holo-Ni(II) HpNikR is a symmetric tetramer containing four canonic square-planar Ni(II) ions at physiological pH

Summary for 2Y3Y

Entry DOI	10.2210/pdb2y3y/pdb
Related	2CA9 2CAD 2CAJ 2WVB 2WVC 2WVD 2WVE 2WVF
Descriptor	PUTATIVE NICKEL-RESPONSIVE REGULATOR, UNDECAPEPTIDE-GSSSGSASGAG, NICKEL (II) ION, ... (6 entities in total)
Functional Keywords	transcription, metal binding
Biological source	HELICOBACTER PYLORI G27 More
Total number of polymer chains	5
Total formula weight	43568.69
Authors	Benini, S.,Cianci, M.,Ciurli, S. (deposition date: 2011-01-04, release date: 2011-08-17, Last modification date: 2024-05-08)
Primary citation	Benini, S.,Cianci, M.,Ciurli, S. Holo-Ni(2+)Helicobacter Pylori Nikr Contains Four Square-Planar Nickel-Binding Sites at Physiological Ph. Dalton Trans, 40:7831-, 2011 Cited by PubMed Abstract: The crystal structure of Helicobacter pylori holo-NikR, a Ni(2+)-dependent transcription factor, determined at pH 7.3, shows four square-planar nickel-binding sites, involving one cysteinate and three histidine ligands. This observation reconciles previous inconsistencies among calorimetric data, structural information at non-physiological pH, and computational studies. PubMed: 21725560 DOI: 10.1039/C1DT11107H PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.39 Å)

Structure validation