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2Y2K

PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (ZA5)

Summary for 2Y2K
Entry DOI10.2210/pdb2y2k/pdb
Related2UWX 2XD1 2XD5 2Y2G 2Y2H 2Y2I 2Y2J 2Y2L 2Y2M 2Y2N 2Y2O 2Y2P 2Y2Q
DescriptorPENICILLIN-BINDING PROTEIN 1B, [(2,6-DIFLUOROPHENYL)CARBONYLAMINO]METHYL-TRIHYDROXY-BORON, SULFATE ION, ... (7 entities in total)
Functional Keywordstransferase, infection, cell wall, peptidoglycan, inhibitor
Biological sourceSTREPTOCOCCUS PNEUMONIAE
Total number of polymer chains1
Total formula weight55112.70
Authors
Contreras-Martel, C.,Amoroso, A.,Woon, E.,Zervosen, A.,Inglis, S.,Martins, A.,Verlaine, O.,Rydzik, A.,Job, V.,Luxen, A.,Joris, B.,Schofield, C.,Dessen, A. (deposition date: 2010-12-15, release date: 2011-08-03, Last modification date: 2023-12-20)
Primary citationContreras-Martel, C.,Amoroso, A.,Woon, E.C.,Zervosen, A.,Inglis, S.,Martins, A.,Verlaine, O.,Rydzik, A.,Job, V.,Luxen, A.,Joris, B.,Schofield, C.J.,Dessen, A.
Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa).
Acs Chem.Biol, 6:943-, 2011
Cited by
PubMed: 21732689
DOI: 10.1021/CB2001846
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.09 Å)
Structure validation

217705

건을2024-03-27부터공개중

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