2Y2G
PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (A01)
Summary for 2Y2G
Entry DOI | 10.2210/pdb2y2g/pdb |
Related | 2UWX 2XD1 2XD5 2Y2H 2Y2I 2Y2J 2Y2K 2Y2L 2Y2M 2Y2N 2Y2O 2Y2P 2Y2Q |
Descriptor | PENICILLIN-BINDING PROTEIN 1B, [(2,6-DIMETHOXYPHENYL)CARBONYLAMINO]METHYL-TRIHYDROXY-BORON, SULFATE ION, ... (7 entities in total) |
Functional Keywords | transferase, infection, cell wall, peptidoglycan, inhibitor |
Biological source | STREPTOCOCCUS PNEUMONIAE |
Total number of polymer chains | 2 |
Total formula weight | 110255.86 |
Authors | Contreras-Martel, C.,Amoroso, A.,Woon, E.C.,Zervosen, A.,Inglis, S.,Martins, A.,Verlaine, O.,Rydzik, A.,Job, V.,Luxen, A.,Joris, B.,Schofield, C.J.,Dessen, A. (deposition date: 2010-12-15, release date: 2011-08-03, Last modification date: 2023-12-20) |
Primary citation | Contreras-Martel, C.,Amoroso, A.,Woon, E.C.,Zervosen, A.,Inglis, S.,Martins, A.,Verlaine, O.,Rydzik, A.,Job, V.,Luxen, A.,Joris, B.,Schofield, C.J.,Dessen, A. Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa). Acs Chem.Biol., 6:943-, 2011 Cited by PubMed: 21732689DOI: 10.1021/CB2001846 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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