2XTK

ChiA1 from Aspergillus fumigatus in complex with acetazolamide

Summary for 2XTK

Entry DOI	10.2210/pdb2xtk/pdb
Descriptor	CLASS III CHITINASE CHIA1, 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	hydrolase, gh18
Biological source	ASPERGILLUS FUMIGATUS
Total number of polymer chains	2
Total formula weight	70137.84
Authors	Schuettelkopf, A.W.,van Aalten, D.M.F. (deposition date: 2010-10-11, release date: 2011-10-26, Last modification date: 2012-08-29)
Primary citation	Schuttelkopf, A.W.,Gros, L.,Blair, D.E.,Frearson, J.A.,Van Aalten, D.M.F.,Gilbert, I.H. Acetazolamide-Based Fungal Chitinase Inhibitors. Bioorg.Med.Chem., 18:8334-, 2010 Cited by PubMed: 21044846 DOI: 10.1016/J.BMC.2010.09.062 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation