2XRC

Human complement factor I

2XRC の概要

• エントリーDOI: 10.2210/pdb2xrc/pdb
• 分子名称: HUMAN COMPLEMENT FACTOR I, CALCIUM ION, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: immune system, hydrolase, conglutinogen activating factor, serine protease, complement system
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Secreted, extracellular space: P05156
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 259336.62

構造登録者

Roversi, P.,Johnson, S.,Lea, S.M. (登録日: 2010-09-13, 公開日: 2011-07-13, 最終更新日: 2023-12-20)

• 主引用文献: Roversi, P.,Johnson, S.,Caesar, J.J.,Mclean, F.,Leath, K.J.,Tsiftsoglou, S.A.,Morgan, B.P.,Harris, C.L.,Sim, R.B.,Lea, S.M.; Structural Basis for Complement Factor I Control and its Disease-Associated Sequence Polymorphisms.; Proc.Natl.Acad.Sci.USA, 108:12839-, 2011; PubMed: 21768352; DOI: 10.1073/PNAS.1102167108

実験手法

X-RAY DIFFRACTION (2.69 Å)