2XR5

Crystal structure of the complex of the carbohydrate recognition domain of human DC-SIGN with pseudo dimannoside mimic.

2XR5 の概要

• エントリーDOI: 10.2210/pdb2xr5/pdb
• 関連するPDBエントリー: 1K9I 1SL4 1SL5 2B6B 2XR6
• 分子名称: CD209 ANTIGEN, alpha-D-mannopyranose, dimethyl (1S,2S,4S,5S)-4,5-dihydroxycyclohexane-1,2-dicarboxylate, ... (7 entities in total)
• 機能のキーワード: sugar binding protein
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 19732.05

構造登録者

Thepaut, M.,Suitkeviciute, I.,Sattin, S.,Reina, J.,Bernardi, A.,Fieschi, F. (登録日: 2010-09-10, 公開日: 2011-10-19, 最終更新日: 2023-12-20)

• 主引用文献: Thepaut, M.,Guzzi, C.,Sutkeviciute, I.,Sattin, S.,Ribeiro-Viana, R.,Varga, N.,Chabrol, E.,Rojo, J.,Bernardi, A.,Angulo, J.,Nieto, P.M.,Fieschi, F.; Structure of a Glycomimetic Ligand in the Carbohydrate Recognition Domain of C-Type Lectin Dc-Sign. Structural Requirements for Selectivity and Ligand Design.; J.Am.Chem.Soc., 135:2518-, 2013; PubMed: 23360500; DOI: 10.1021/JA3053305

実験手法

X-RAY DIFFRACTION (1.42 Å)