2XQ0

Structure of yeast LTA4 hydrolase in complex with Bestatin

Summary for 2XQ0

Entry DOI	10.2210/pdb2xq0/pdb
Related	2XPY 2XPZ
Descriptor	LEUKOTRIENE A-4 HYDROLASE, 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, ZINC ION, ... (5 entities in total)
Functional Keywords	hydrolase
Biological source	SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)
Cellular location	Cytoplasm : Q10740
Total number of polymer chains	1
Total formula weight	73483.77
Authors	Helgstrand, C.,Hasan, M.,Usyal, H.,Haeggstrom, J.Z.,Thunnissen, M.M.G.M. (deposition date: 2010-08-31, release date: 2010-12-29, Last modification date: 2023-12-20)
Primary citation	Helgstrand, C.,Hasan, M.,Usyal, H.,Haeggstrom, J.Z.,Thunnissen, M.M.G.M. A Leukotriene A(4) Hydrolase-Related Aminopeptidase from Yeast Undergoes Induced Fit Upon Inhibitor Binding. J.Mol.Biol., 406:120-, 2011 Cited by PubMed: 21146536 DOI: 10.1016/J.JMB.2010.11.059 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.955 Å)

Structure validation