2XNT
Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures to identify structurally novel ligands for the nicotinic receptors
Summary for 2XNT
Entry DOI | 10.2210/pdb2xnt/pdb |
Related | 2BR7 2BR8 2BYN 2BYP 2BYQ 2BYR 2BYS 2C9T 2UZ6 2W8E 2W8F 2W8G 2WN9 2WNC 2WNJ 2WNL 2WZY 2X00 2XNU 2XNV |
Descriptor | SOLUBLE ACETYLCHOLINE RECEPTOR, (2S)-2-[(4-CHLOROBENZYL)OXY]-2-PHENYLETHANAMINE, BROMIDE ION (3 entities in total) |
Functional Keywords | receptor, choline-binding protein, in-silico screening, ligand-gated ion channels, electrophysiology, cys-loop receptors |
Biological source | APLYSIA CALIFORNICA (CALIFORNIA SEA HARE) |
Total number of polymer chains | 10 |
Total formula weight | 269876.18 |
Authors | Rucktooa, P.,Akdemir, A.,deEsch, I.,Sixma, T.K. (deposition date: 2010-08-06, release date: 2011-08-24, Last modification date: 2023-12-20) |
Primary citation | Akdemir, A.,Rucktooa, P.,Jongejan, A.,Elk, R.V.,Bertrand, S.,Sixma, T.K.,Bertrand, D.,Smit, A.B.,Leurs, R.,De Graaf, C.,De Esch, I.J. Acetylcholine Binding Protein (Achbp) as Template for Hierarchical in Silico Screening Procedures to Identify Structurally Novel Ligands for the Nicotinic Receptors. Bioorg.Med.Chem., 19:6107-, 2011 Cited by PubMed: 21920761DOI: 10.1016/J.BMC.2011.08.028 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.21 Å) |
Structure validation
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