2XML

Crystal structure of human JMJD2C catalytic domain

Summary for 2XML

• Entry DOI: 10.2210/pdb2xml/pdb
• Related: 2XDP
• Descriptor: LYSINE-SPECIFIC DEMETHYLASE 4C, N-OXALYLGLYCINE, NICKEL (II) ION, ... (7 entities in total)
• Functional Keywords: oxidoreductase, transcription regulation, metal binding
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Nucleus : Q9H3R0
• Total number of polymer chains: 2
• Total formula weight: 81694.37

Authors

Yue, W.W.,Gileadi, C.,Krojer, T.,Pike, A.C.W.,von Delft, F.,Ng, S.,Carpenter, L.,Arrowsmith, C.,Weigelt, J.,Edwards, A.,Bountra, C.,Oppermann, U. (deposition date: 2010-07-28, release date: 2010-09-29, Last modification date: 2023-12-20)

• Primary citation: Hillringhaus, L.,Yue, W.W.,Rose, N.R.,Ng, S.S.,Gileadi, C.,Loenarz, C.,Bello, S.H.,Bray, J.E.,Schofield, C.J.,Oppermann, U.; Structural and Evolutionary Basis for the Dual Substrate Selectivity of Human Kdm4 Histone Demethylase Family.; J.Biol.Chem., 286:41616-, 2011; PubMed: 21914792; DOI: 10.1074/JBC.M111.283689

Experimental method

X-RAY DIFFRACTION (2.55 Å)