2XJC
Crystal structure of the D52N variant of cytosolic 5'-nucleotidase II in complex with guanosine monophosphate and diadenosine tetraphosphate
Summary for 2XJC
Entry DOI | 10.2210/pdb2xjc/pdb |
Related | 2J2C 2JC9 2JCM 2XCV 2XCW 2XCX 2XJB 2XJD 2XJE 2XJF |
Descriptor | CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GUANOSINE-5'-MONOPHOSPHATE, BIS(ADENOSINE)-5'-TETRAPHOSPHATE, ... (6 entities in total) |
Functional Keywords | allosteric enzyme, cn-ii, gmp-imp specific nucleotidase, high km 5-prime nucleotidase, hydrolase, metal-binding, nt5c2, nucleotide metabolism, nucleotide-binding, phosphoprotein |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm: P49902 |
Total number of polymer chains | 1 |
Total formula weight | 65917.41 |
Authors | Wallden, K.,Nordlund, P. (deposition date: 2010-07-03, release date: 2011-03-16, Last modification date: 2023-12-20) |
Primary citation | Wallden, K.,Nordlund, P. Structural Basis for the Allosteric Regulation and Substrate Recognition of Human Cytosolic 5'-Nucleotidase II J.Mol.Biol., 408:684-, 2011 Cited by PubMed: 21396942DOI: 10.1016/J.JMB.2011.02.059 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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