2XIJ

Crystal structure of human methylmalonyl-CoA mutase in complex with adenosylcobalamin

2XIJ の概要

• エントリーDOI: 10.2210/pdb2xij/pdb
• 関連するPDBエントリー: 2XIQ
• 分子名称: METHYLMALONYL-COA MUTASE, MITOCHONDRIAL, 5'-DEOXYADENOSINE, SULFATE ION, ... (7 entities in total)
• 機能のキーワード: isomerase, organic aciduria, vitamin b12
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Mitochondrion matrix: P22033
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 87315.33

構造登録者

Yue, W.W.,Froese, D.S.,Kochan, G.,Chaikuad, A.,Krojer, T.,Muniz, J.,Vollmar, M.,Arrowsmith, C.,Weigelt, J.,Edwards, A.,Bountra, C.,Oppermann, U. (登録日: 2010-06-30, 公開日: 2010-09-29, 最終更新日: 2023-12-20)

• 主引用文献: Froese, D.S.,Kochan, G.,Muniz, J.,Wu, X.,Gileadi, C.,Ugochukwu, E.,Krysztofinska, E.,Gravel, R.A.,Oppermann, U.,Yue, W.W.; Structures of the Human Gtpase Mmaa and Vitamin B12-Dependent Methylmalonyl-Coa Mutase and Insight Into Their Complex Formation.; J.Biol.Chem., 285:38204-, 2010; PubMed: 20876572; DOI: 10.1074/JBC.M110.177717

実験手法

X-RAY DIFFRACTION (1.95 Å)