2XEI

Human glutamate carboxypeptidase II in complex with Antibody- Recruiting Molecule ARM-P2

2XEI の概要

• エントリーDOI: 10.2210/pdb2xei/pdb
• 関連するPDBエントリー: 1Z8L 2C6C 2C6G 2C6P 2CIJ 2JBJ 2JBK 2XEF 2XEG 2XEJ
• 分子名称: GLUTAMATE CARBOXYPEPTIDASE 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: metallopeptidase, hydrolase
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Cell membrane ; Single-pass type II membrane protein . Isoform PSMA': Cytoplasm: Q04609
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 83407.49

構造登録者

Zhang, A.X.,Murelli, R.P.,Barinka, C.,Michel, J.,Cocleaza, A.,Jorgensen, W.L.,Lubkowski, J.,Spiegel, D.A. (登録日: 2010-05-14, 公開日: 2010-09-08, 最終更新日: 2023-12-20)

• 主引用文献: Zhang, A.X.,Murelli, R.P.,Barinka, C.,Michel, J.,Cocleaza, A.,Jorgensen, W.L.,Lubkowski, J.,Spiegel, D.A.; A Remote Arene-Binding Site on Prostate Specific Membrane Antigen Revealed by Antibody-Recruiting Small Molecules.; J.Am.Chem.Soc., 132:12711-, 2010; PubMed: 20726553; DOI: 10.1021/JA104591M

実験手法

X-RAY DIFFRACTION (1.69 Å)