2XED

Nocardia farcinica maleate cis-trans isomerase C194S mutant with a covalently bound succinylcysteine intermediate

Summary for 2XED

• Entry DOI: 10.2210/pdb2xed/pdb
• Related: 2XEC
• Descriptor: PUTATIVE MALEATE ISOMERASE, SUCCINIC ACID (3 entities in total)
• Functional Keywords: isomerase, nicotinic acid catabolism, cofactor-independent cis-trans isomerase
• Biological source: NOCARDIA FARCINICA
• Total number of polymer chains: 4
• Total formula weight: 115780.25

Authors

Fisch, F.,Martinez-Fleites, C.,Baudendistel, N.,Hauer, B.,Turkenburg, J.P.,Hart, S.,Bruce, N.C.,Grogan, G. (deposition date: 2010-05-13, release date: 2010-08-18, Last modification date: 2023-12-20)

• Primary citation: Fisch, F.,Fleites, C.M.,Delenne, M.,Baudendistel, N.,Hauer, B.,Turkenburg, J.P.,Hart, S.,Bruce, N.C.,Grogan, G.; A Covalent Succinylcysteine-Like Intermediate in the Enzyme-Catalyzed Transformation of Maleate to Fumarate by Maleate Isomerase.; J.Am.Chem.Soc., 132:11455-, 2010; PubMed: 20677745; DOI: 10.1021/JA1053576

Experimental method

X-RAY DIFFRACTION (1.95 Å)