2XDE

Crystal structure of the complex of PF-3450074 with an engineered HIV capsid N terminal domain

Summary for 2XDE

Entry DOI	10.2210/pdb2xde/pdb
Descriptor	GAG POLYPROTEIN, N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE (3 entities in total)
Functional Keywords	aids, viral protein
Biological source	HUMAN IMMUNODEFICIENCY VIRUS 1
Total number of polymer chains	2
Total formula weight	33286.03
Authors	Brown, D.G.,Irving, S.L.,Anderson, M.,Bazin, R. (deposition date: 2010-04-30, release date: 2010-12-22, Last modification date: 2019-05-22)
Primary citation	Blair, W.S.,Pickford, C.,Irving, S.L.,Brown, D.G.,Anderson, M.,Bazin, R.,Cao, J.,Ciaramella, G.,Isaacson, J.,Jackson, L.,Hunt, R.,Kjerrstrom, A.,Nieman, J.,Patick, A.K.,Perros, M.,Scott, A.D.,Whitby, K.,Wu, H.,Butler, S.L. HIV Capsid is a Tractable Target for Small Molecule Therapeutic Intervention. Plos Pathog., 6:E1220-, 2010 Cited by PubMed: 21170360 DOI: 10.1371/JOURNAL.PPAT.1001220 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation