2XCG

Tranylcypromine-inhibited human monoamine oxidase B in complex with 2- (2-benzofuranyl)-2-imidazoline

2XCG の概要

• エントリーDOI: 10.2210/pdb2xcg/pdb
• 関連するPDBエントリー: 1GOS 1H8R 1OJ9 1OJA 1OJB 1OJC 1OJD 1S2Q 1S2Y 1S3B 1S3E 2BK3 2BK4 2BK5 2BYB 2C64 2C65 2C66 2C67 2C70 2C72 2C73 2C75 2C76 2V5Z 2V60 2V61 2VRL 2VRM 2VZ2
• 分子名称: Amine oxidase [flavin-containing] B, [[(2R,3S,4S)-5-[(4AS)-7,8-DIMETHYL-2,4-DIOXO-4A,5-DIHYDROBENZO[G]PTERIDIN-10-YL]-2,3,4-TRIHYDROXY-PENTOXY]-HYDROXY-PHOSPHORYL] [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL HYDROGEN PHOSPHATE, 3-PHENYLPROPANAL, ... (6 entities in total)
• 機能のキーワード: flavoprotein, maob, mitochondrion, oxidoreductase, transmembrane
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 120560.44

構造登録者

Bonivento, D.,Milczek, E.M.,McDonald, G.R.,Binda, C.,Holt, A.,Edmondson, D.E.,Mattevi, A. (登録日: 2010-04-23, 公開日: 2010-10-06, 最終更新日: 2023-12-20)

• 主引用文献: Bonivento, D.,Milczek, E.M.,McDonald, G.R.,Binda, C.,Holt, A.,Edmondson, D.E.,Mattevi, A.; Potentiation of ligand binding through cooperative effects in monoamine oxidase B.; J. Biol. Chem., 285:36849-36856, 2010; PubMed: 20855894; DOI: 10.1074/jbc.M110.169482

実験手法

X-RAY DIFFRACTION (1.9 Å)