2XB2
Crystal structure of the core Mago-Y14-eIF4AIII-Barentsz-UPF3b assembly shows how the EJC is bridged to the NMD machinery
Summary for 2XB2
| Entry DOI | 10.2210/pdb2xb2/pdb |
| Related | 1P27 1UW4 2J0Q 2J0S 2J0U |
| Descriptor | EUKARYOTIC INITIATION FACTOR 4A-III, PROTEIN MAGO NASHI HOMOLOG, RNA-BINDING PROTEIN 8A, ... (9 entities in total) |
| Functional Keywords | exon junction complex, nonsense-mediated mrna decay, translation, upf3b, hydrolase |
| Biological source | HOMO SAPIENS (HUMAN) More |
| Cellular location | Nucleus: P38919 P61326 Q9Y5S9 Q9BZI7 Cytoplasm, perinuclear region: O15234 |
| Total number of polymer chains | 13 |
| Total formula weight | 208445.59 |
| Authors | Buchwald, G.,Ebert, J.,Basquin, C.,Sauliere, J.,Jayachandran, U.,Bono, F.,Le Hir, H.,Conti, E. (deposition date: 2010-04-03, release date: 2010-05-12, Last modification date: 2023-12-20) |
| Primary citation | Buchwald, G.,Ebert, J.,Basquin, C.,Sauliere, J.,Jayachandran, U.,Bono, F.,Le Hir, H.,Conti, E. Insights Into the Recruitment of the Nmd Machinery from the Crystal Structure of a Core Ejc-Upf3B Complex. Proc.Natl.Acad.Sci.USA, 107:10050-, 2010 Cited by PubMed: 20479275DOI: 10.1073/PNAS.1000993107 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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